生成式 AI 与患者沟通

The article discusses a study conducted by Lizak and colleagues, which aimed to evaluate the impact of highly active immunomodulatory therapy on the progression of moderately advanced and advanced multiple sclerosis (MS) 1. The study used data from over 4,000 patients with MS and found that the disability trajectories showed large variability. The probability of reaching the outcome was not associated with baseline variables, suggesting that previous disease activity before progress into advanced stages does not have a significant impact on later disease progression. However, higher relapsed rate was associated with disability. Additionally, highly active immunomodulatory therapy was associated with lower risk of reaching the outcome disability step 1. The authors conclude that disease progression in moderately advanced and advanced MS is highly variable and amnesic to prior disease activity. Lower relapse rates and greater time with active immunomodulatory therapy are associated with decreased risk of accumulating further disability. Highly active immunomodulatory therapy may delay disability in moderately advanced and advanced multiple sclerosis 1.

1：https://blogs.bmj.com/jnnp/2017/03/05/­­immunomodulatory-therapy-modulates-progression-in-advanced-multiple-sclerosis/

The article talks about a study that looked at how a certain type of treatment affects the progression of multiple sclerosis (MS). The study found that the treatment can help delay disability in people with moderately advanced and advanced MS. The study also found that the risk of disability was lower in people who had fewer relapses and were on the treatment for a longer time. The authors suggest that this treatment may be helpful for people with moderately advanced and advanced MS.