Watch: COA Translation and 5 Common COA Challenges

COAs often precipitate clinical trial translation challenges with rare languages, data quality, rater training, regulatory compliance, and eCOA migration. This blog shares a video about how Lionbridge’s COA translation and eCOA translation services (including linguistic validation services) can help clinical trial sponsors tackle these five challenges. The video is structured around answers to customer questions around these challenging areas.

Linguistic Validation Services for Rare Languages

The first question answered is about whether linguistic validation services differ for rare languages. Especially at Lionbridge, these services vary slightly to help ensure accurate, reliable results. While the core process remains, the approach is carefully tailored to each language. It may require more forward planning and transparency to accommodate a need for local and remote experts. Lionbridge also taps into its Community Management team and global network to find the ideal linguists for very niche and long-tail languages.

COA Translation Services for Better Data

Secondly, the video covers how Lionbridge’s COA translation services ensure COAs collect high-quality, complete data from diverse patient populations. These are the measures we take:

• Performing linguistic validation and cultural adaptation

• Reducing bias via translatability assessments, expert reviews, and iterative translations

• Conducting cognitive debriefing with diverse participants to confirm COAs are understandable and relevant

COA Translation Services and Rater Training

Next, the video addresses how Lionbridge’s clinical trial translation team supports Rater Training for consistency and accuracy across study sites. We achieve this goal by structuring COA administration instructions for clinicians, researchers, and site staff who administer COAs. This minimizes variability and bias. To fully support training, we translate materials, subtitles, voiceovers, and interactive Storyline courses. We even have dedicated eLearning project managers experienced in best practices for Rater Training.